Visual quality of life in NMOSD and MOGAD: profiles, dynamics and associations with ageing and vision
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Acute suppression of mitochondrial ATP production prevents apoptosis and provides an essential signal for NLRP3 inflammasome activation
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Single Cell Deletion of the Transcription Factors Trps1 and Sox9 in Astrocytes Reveals Novel Functions in the Adult Cerebral Cortex
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Mechanotransduction governs CD40 function and underlies X-linked hyper-IgM syndrome
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Mitochondrial calcium uniporter complex controls T-cell-mediated immune responses
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Neuroinflammation in Alzheimer disease
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Apolipoprotein E aggregation in microglia initiates Alzheimer’s disease pathology by seeding β-amyloidosis
doi: 10.1016/j.immuni.2024.09.014
Comparing Viral Vectors and Fate Mapping Approaches for Astrocyte-to-Neuron Reprogramming in the Injured Mouse Cerebral Cortex
doi: 10.3390/cells13171408
Dynamic Brain Lipid Profiles Modulate Microglial Lipid Droplet Accumulation and Inflammation Under Ischemic Conditions in Mice
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White matter aging and its impact on brain function
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Nonvesicular lipid transfer drives myelin growth in the central nervous system
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Apheresis therapies in MOGAD: a retrospective study of 117 therapeutic interventions in 571 attacks
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Towards Treating Multiple Sclerosis Progression
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BCAS1-positive oligodendrocytes enable efficient cortical remyelination in multiple sclerosis
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Twin study identifies early immunological and metabolic dysregulation of CD8+ T cells in multiple sclerosis
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Adaptive digital tissue deconvolution.
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CODEX: COunterfactual Deep learning for the in silico EXploration of cancer cell line perturbations.
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TFEB activation hallmarks antigenic experience of B lymphocytes and directs germinal center fate decisions
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Combining array tomography with electron tomography provides insights into leakiness of the blood-brain barrier in mouse cortex.
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Innate immune memory after brain injury drives inflammatory cardiac dysfunction
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Astrocytes adopt a progenitor-like migratory strategy for regeneration in adult brain
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Erythropoietin restrains the inhibitory potential of interneurons in the mouse hippocampus
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Toward identifying key mechanisms of progression in multiple sclerosis
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Association of retinal vessel pathology and brain atrophy in relapsing-remitting multiple sclerosis
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Unrestrained cleavage of Roquin-1 by MALT1 induces spontaneous T cell activation and the development of autoimmunity
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The role of intrathecal free light chains kappa for the detection of autoimmune encephalitis in subacute onset neuropsychiatric syndromes
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Reactive oxygen species produced by myeloid cells in psoriasis as a potential biofactor contributing to the development of vascular inflammation
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Foxp3+ regulatory T cells in the central nervous system and other nonlymphoid tissues
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Evaluation of Novel Enhancer Compounds in Gentamicin-Mediated Readthrough of Nonsense Mutations in Rett Syndrome
doi: 10.3390/ijms241411665
3d Virtual Histology Reveals Pathological Alterations of Cerebellar Granule Cells in Multiple Sclerosis
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Rapid differentiation of MOGAD and MS after a single optic neuritis
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Oligodendroglial fatty acid metabolism as a central nervous system energy reserve
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Accelerometer-derived movement features as predictive biomarkers for muscle atrophy in neurocritical care: a prospective cohort study
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Diagnostic accuracy and confounders of vagus nerve ultrasound in amyotrophic lateral sclerosis—a single-center case series and pooled individual patient data meta-analysis
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Innate immune training restores pro-reparative myeloid functions to promote remyelination in the aged central nervous system
doi: 10.1016/j.immuni.2024.07.001
Neurofilament Light Chain Serum Levels Mirror Age and Disability in Secondary Progressive Multiple Sclerosis
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Direct neuronal reprogramming of mouse astrocytes is associated with multiscale epigenome remodeling and requires Yy1
doi: 10.1038/s41593-024-01677-5
T cell-mediated microglial activation triggers myelin pathology in a mouse model of amyloidosis
doi: 10.1038/s41593-024-01682-8
Tolerability and first hints for potential efficacy of motor‐cognitive training under inspiratory hypoxia in health and neuropsychiatric disorders: A translational viewpoint
doi: 10.1002/nep3.47
Multiple sclerosis and the intestine: Chasing the microbial offender
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Retinal small vessel pathology is associated with disease burden in multiple sclerosis
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Optical coherence tomography angiography suggests different retinal pathologies in multiple sclerosis and Sjögren’s syndrome
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BTK inhibition limits microglia-perpetuated CNS inflammation and promotes myelin repair
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Cerebellar Ex Vivo Magnetic Resonance Imaging at its Feasibility Limit: Up to 77-Microns Isotropic Resolution using Low-Bandwidth Balanced Steady State Free Precession (LoBa-bSSFP) Sequences and 3T Standard Equipment
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Fluorogenic Chemical Probes for Wash-free Imaging of Cell Membrane Damage in Ferroptosis, Necrosis, and Axon Injury
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Shared inflammatory glial cell signature after stab wound injury, revealed by spatial, temporal, and cell-type-specific profiling of the murine cerebral cortex
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Gut–Brain Interactions and Their Impact on Astrocytes in the Context of Multiple Sclerosis and Beyond
doi: 10.3390/cells13060497
Polyglutamylation of microtubules drives neuronal remodeling
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An Animal Model for Chronic Meningeal Inflammation and Inflammatory Demyelination of the Cerebral Cortex
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Risk factors and outcomes after interruption of sedation in subarachnoid hemorrhage (ROUTINE-SAH) -a retrospective cohort study
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The astrocyte-produced growth factor HB-EGF limits autoimmune CNS pathology
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Differential Role of Factor XIII in Acute Myocardial Infarction and Ischemic Stroke
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Plasma Lipidomic Profiling Using Mass Spectrometry for Multiple Sclerosis Diagnosis and Disease Activity Stratification (LipidMS)
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Oligodendrocytes produce amyloid-β and contribute to plaque formation alongside neurons in Alzheimer’s disease model mice
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B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4
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In-situ architecture of the human prohibitin complex
doi: 10.1101/2024.02.14.579514
Validating a minipig model of reversible cerebral demyelination using human diagnostic modalities and electron microscopy
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IntelliR: A comprehensive and standardized pipeline for automated profiling of higher cognition in mice
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Direct neuronal reprogramming of NDUFS4 patient cells identifies the unfolded protein response as a novel general reprogramming hurdle
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Long term follow-up in GAMT deficiency – Correlation of therapy regimen, biochemical and in vivo brain proton MR spectroscopy data
doi: 10.1016/j.ymgmr.2024.101053
L-Lactate Treatment at 24 h and 48 h after Acute Experimental Stroke Is Neuroprotective via Activation of the L-Lactate Receptor HCA1
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Folate receptor α deficiency – Myelin‐sensitive MRI as a reliable biomarker to monitor the efficacy and long‐term outcome of a new therapeutic approach
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CSF and venous blood flow from childhood to adulthood studied by real-time phase-contrast MRI
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Characteristics, Prevalence, and Clinical Relevance of Juxtacortical Paramagnetic Rims in Patients With Multiple Sclerosis
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Injury-specific factors in the cerebrospinal fluid regulate astrocyte plasticity in the human brain
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Sekundärprophylaxe des ischämischen Schlaganfalls
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Early Neuroaxonal Damage in Neurologic Disorders Associated With GAD65 Antibodies
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Targeting the TCA cycle can ameliorate widespread axonal energy deficiency in neuroinflammatory lesions
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A genome-wide in vivo CRISPR screen identifies essential regulators of T cell migration to the CNS in a multiple sclerosis model
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PD-L1 positive astrocytes attenuate inflammatory functions of PD-1 positive microglia in models of autoimmune neuroinflammation
doi: 10.1038/s41467-023-40982-8
Fibroblast growth factor 9 (FGF9) mediated neurodegeneration: implications for progressive multiple sclerosis?
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Expanding the function of oligodendrocytes to brain energy metabolism
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Erythropoietin re-wires cognition-associated transcriptional networks
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Regulation of the programmed cell death protein 1/programmed cell death ligand 1axis in relapsing-remitting multiple sclerosis
doi: 10.1093/braincomms/fcad206
Immune-mediated denervation of the pineal gland underlies sleep disturbance in cardiac disease
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Proceedings of the National Academy of Sciences of the United States of America
2023
Pubmed
Open AccessJournal Article
Visualizing the activation of encephalitogenic T cells in the ileal lamina propria by in vivo two-photon imaging
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Spatial Transcriptomics-correlated Electron Microscopy maps transcriptional and ultrastructural responses to brain injury
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Tipping points in neurodegeneration
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Myelin insulation as a risk factor for axonal degeneration in autoimmune demyelinating disease
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Ex vivo immunocapture and functional characterization of cell-type-specific mitochondria using MitoTag mice
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Myelin dysfunction drives amyloid-β deposition in models of Alzheimer’s disease
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2-Methoxyestradiol-3,17-O,O-bis-sulfamate inhibits store-operated Ca(2+) entry in T lymphocytes and prevents experimental autoimmune encephalomyelitis.
doi: 10.1016/j.bbamcr.2023.119485
Neural dynamics and architecture of the heading direction circuit in zebrafish.
doi: 10.1038/s41593-023-01308-5
Remyelination by surviving oligodendrocytes is inefficient in the inflamed mammalian cortex.
doi: 10.1016/j.neuron.2023.03.031
Myelination generates aberrant ultrastructure that is resolved by microglia.
doi: 10.1083/jcb.202204010
Shared inflammatory glial cell signature after brain injury, revealed by spatial, temporal and cell-type-specific profiling of the murine cerebral cortex
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Exploiting moderate hypoxia to benefit patients with brain disease: Molecular mechanisms and translational research in progress
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Antibodies Against Glutamic Acid Decarboxylase 65 Are Locally Produced in the CSF and Arise During Affinity Maturation
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Membrane lipid remodeling modulates γ-secretase processivity
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Drug screening identifies tazarotene and bexarotene as therapeutic agents in multiple sulfatase deficiency
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Targeting B Cells and Microglia in Multiple Sclerosis With Bruton Tyrosine Kinase Inhibitors
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Heterogeneity of neurons reprogrammed from spinal cord astrocytes by the proneural factors Ascl1 and Neurogenin2
doi: 10.1016/j.celrep.2021.109409
Multi-color live-cell STED nanoscopy of mitochondria with a gentle inner membrane stain
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Targeted metabolomics revealed changes in phospholipids during the development of neuroinflammation in Abcd1tm1Kds mice and X‐linked adrenoleukodystrophy patients
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LC-MS Based Platform Simplifies Access to Metabolomics for Peroxisomal Disorders
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Urinary Levels of SARS-CoV-2 Nucleocapsid Protein Associate With Risk of AKI and COVID-19 Severity: A Single-Center Observational Study
doi: 10.3389/fmed.2021.644715
The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells
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Neuronal replacement: Concepts, achievements, and call for caution
doi: 10.1016/j.conb.2021.03.014
Correction: Heterogeneity of neurons reprogrammed from spinal cord astrocytes by the proneural factors Ascl1 and Neurogenin2
doi: 10.1016/j.celrep.2021.109571
TUNAR lncRNA Encodes a Microprotein that Regulates Neural Differentiation and Neurite Formation by Modulating Calcium Dynamics
doi: 10.3389/fcell.2021.747667
